Human Liver Microsomes (Pool-100)
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Specifications
- 10 mg of protein/vial, 0,5 mL
- Batch size >1000 vials
- Total CYP > 200 ng/mg of protein
- Verapamil, Clint (uL/min/mg), 3A4 250 350
- Testosterone, Clint (uL/min/mg), 3A4 60 120
- Diclofenac, Clint (uL/min/mg), 2C9 180 360
- Phenacetin, Clint (uL/min/mg), 1A2 20 40
- Imipramine, Clint (uL/min/mg), 2C19 15 35
- Benzydimine, Clint (uL/min/mg), FMO 10
- Metoprolol, Clint (uL/min/mg), 2D6 5 15
Description
Our 100-donor pooled human liver microsomes offer an advanced and highly representative metabolic model for comprehensive drug metabolism studies. With microsomes pooled from 100 individual donors, this product provides an extensive metabolic profile that reflects a broader genetic and phenotypic diversity, increasing the relevance and predictability of in vitro findings to real-world populations.
