hi@preci.care
hi@preci.care
Preci Preci
Next era of disease modeling

In drug discovery and disease research, primary cell models are essential for accurately mimicking human biology, offering a more physiologically relevant alternative to traditional cell lines and animal models. Preci’s solutions go beyond providing advanced ECM scaffolds by focusing on overcoming key challenges in primary cell modeling, such as donor-to-donor variability and scalability. Preci’s innovative microfluidic spheroid generation technology addresses these challenges by producing highly homogeneous spheroids with a precisely controlled number of cells.

This high-throughput process can generate over 5,000 microspheres per hour, enabling reliable, reproducible models that better reflect human disease mechanisms and drug responses. By enhancing the precision and scalability of primary cell models, Preci helps bridge the gap between preclinical studies and clinical outcomes, ultimately supporting the development of safer, more effective therapeutics.With these powerful tools, Preci enables researchers to optimize their studies and achieve more accurate predictions of drug efficacy, toxicity, and metabolism, driving innovation and efficiency in drug discovery and disease research.

Сustom cell isolation

Primary cell products are increasingly used in drug discovery due to their ability to more accurately reflect human biological processes compared to immortalized cell lines or animal models. These cells retain the physiological characteristics of their tissue of origin, providing a closer approximation of human responses to drug candidates.

This is particularly important in studying disease mechanisms, toxicity, drug metabolism, and efficacy. As a result, primary cell models reduce the translational gap between preclinical studies and clinical outcomes, enhancing the success rate of drug development while reducing costs and time to market.

  1. Tissue procurement

    Tissue procurement for primary cell modeling typically involves a highly controlled process to ensure the quality and viability of the biospecimens.

  2. Isolation procedure optimization

    Tissue digestion optimization is a critical step in isolating viable primary cells from solid tissues, and it involves fine-tuning multiple parameters to balance yield, cell viability, and functionality.

  3. Cell purification and identification

    After tissue digestion, primary cells are purified and identified through a series of steps to ensure a high-quality, homogeneous population.

  4. Quality control and storage

    Properly validated QC and storage protocols ensure that the cells retain their viability and functionality for reliable, reproducible research.

Adherence to stringent QC and optimized storage protocols is essential for generating high-quality primary cell models, which are critical for accurate drug discovery. Maintaining cell viability, functionality, and phenotypic stability throughout isolation, purification, and storage ensures that these models reliably mimic in vivo human biology.

Each step—whether optimizing tissue digestion, purifying cells with high specificity, or employing advanced QC measures—directly influences the cells’ performance in assays, including their metabolic activity, response to drugs, and genetic integrity. Deviation from these principles can lead to compromised cell quality, resulting in unreliable data or failed experiments.

View All Products

Ask for a presentation Contact us

Please fill up the form below