Preci Preci

Kidney diseases

Kidney disease impact glomerular homeostasis and can lead to irreversible damage to an organism. Kidney frequently accumulates antibody complexes, bound toxins and undergoes inflammation. All of those processes require careful investigation. Therefore, we have developed our glomerular organoid systems, which can be matched with the patient-derived PBMC to model immune cell activation and its effect to the tissue

Glomerular epithelial and endothelial, kidney fibroblasts hECM-embedded organoids

Rheumatoid Arthritis conditions modelling set components

Renal disease range

  • Renal Failure
  • Kidney Fibrosis
  • Renal Inflammatory Syndromes

Assays validated

  • RNAseq and target expression analysis
  • Inflammation cytokines sectretion
  • T-cell activation
  • Cell killing

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