Inflammatory bowel disease is a complex highly multicomponent disease, which harms a very high population of patients. Inflammation is highly diverse and involves epithelial, stromal, and immune cells cross-talk. It is highly essential to account for all disease components to figure out the potential therapeutic approaches. Preci offers crypt-based models, qualified for the organoid formation along with the patient’s native immune cells, and also its own ECM-embedded models, incorporating stromal and epithelial cells
ECM-embedded stroma/epithelium organoids
IBD/Ulcerative colitis modelling set components
Intestinal disease range
- Inflammatory Bowel Syndrome
- Ulcerative colitis
Assays validated
- RNAseq and target expression analysis
- Inflammation cytokines sectretion
- T-cell activation
- Cell killing