IDC-Derived Cultured Cells
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Specifications
- 1 mln cells/vial
- Post-thaw viability - ≥ 80%
- ≥ 90% CD11c+, ≥ 90% MHC class II+, ≤ 30% CD83+, and ≤ 5% CD14high by flow cytometry
Description
Our human immune dendritic cells are mature dendritic cells derived from peripheral blood monocytes of ethically consented donors. These cells are generated in vitro by culturing monocytes with GM-CSF and IL-4, followed by maturation using immunostimulatory agents such as LPS, TNF-α, or a cytokine cocktail. The resulting mature dendritic cells exhibit high expression of co-stimulatory molecules (CD80, CD83, CD86) and MHC class II, making them ideal for studies involving T-cell activation, immune response modulation, and antigen presentation.
These immune-competent dendritic cells are widely used in cancer immunotherapy, infectious disease modeling, vaccine adjuvant screening, and T-cell co-culture assays
