Preci Preci

Solid tumors

Oncological disease modelling suffers from multiple problems, such as low success rate, trade-off of complexity for technical cumbersomeness, and inability to model tumor microenvironment. Role of cancer-associated fibroblasts and immune component has been long overlooked in models, despite the obvious demand from the drug discovery scientists. Preci’s self-assembled ECM-embedded organoids offer platform for the testing of drug activity, target engangement, specificity and many more effects on a whole tumor cells complexity without sacrificing technical simplicity. We offer isogenic models, incorporating cancer cells, endothelial components, cancer-associated fibroblasts, and PBMCs, which takes only mixing to assemble.

Assembly into complex tumoroid

Solid tumors modelling set components

Tumor diversity

  • Non-small cell lung cancer
  • Colorectal Cancer
  • Gynaecological tumors
  • Small cell lung cancer
  • Stomach Cancer
  • Hepatocellular Carcinoma
  • Breast Cancer
  • Pancreatic cancer
  • Melanoma
  • Prostate Cancer
  • Head and Neck Tumors
  • Bladder cancer

Assays validated

  • RNAseq and target expression analysis
  • Cell killing assays
  • Apoptosis
  • Cell ratio (imaging-based)
  • Proliferation
  • T-cell activation

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