Human-Relevant In Vitro Models for Better Drug Discovery
From human-derived extracellular matrix to advanced organoids. We build translational models that better reflect native tissue biology.
“The best assays and disease models identified good drugs, which succeeded in clinical trials, entered widespread clinical use, became generic, raised the commercial barriers to new R&D and so rendered the best models industrially redundant.”
Nature article
Fit-for-Purpose Tumor Modeling
Тumor heterogeneity and complex tumor behavior require fit-for-purpose model selection. Different research goals demand different levels of biological complexity.
Analytical/Tissue Models
FFPE/Frozen Tissue
molecular analysis
Living/Functional (2D and ex vivo)
tissue analysis, native architecture
human heterogeneity and relevance
3D/Microenvironment
cell-cell interaction
self-organized tissue model
native microenvironment
Broad applications across therapeutic areas
Oncology
Tumor heterogeneity, responce profiling, mechanism of action
Metabolic disease
Liver, adipose, gut and pancreatic disease modeling
Fibrosis
Matrix remodeling, myofibroblast biology, anti-fibrotic testing
Immunology
Immune-tissue interaction, inflammation
Drug safety
Off-targets effect, safety pharmacology
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