Insights & Innovations

Traditional 2D culture and animal models miss key signals from the extracellular matrix — one reason drugs that work in early testing fail in humans. Here's how human ECM is used in 2D coatings, spheroids, and contraction assays to build more predictive in vitro models for cancer and fibrosis research.

Self-assembling hydrogels gel with nothing but thermodynamics — no cross-linker, no UV. Here's how they work, where they're already used in drug delivery and tissue models, and how a new graph-based imaging method quantifies the network structure behind performance.

A co-immunoprecipitation assay captures protein-protein interactions under native cellular conditions. This guide covers the full Co-IP workflow, its use in small-molecule target engagement, and key analytical limitations.

Download Preci's Disease Modeling Platforms brochure. A comprehensive overview of OncoPlatform™, AIDPlatform™, and FMCPlatform™ for oncology, autoimmune, and metabolic disease research.

This guide covers the complete gel contraction assay workflow, including protocol setup, Young’s modulus quantification, troubleshooting, and interpretation of contraction results.

Cell-matrix interactions control how tissues organize, change shape, and respond to signals. Understanding properties like tissue fluidity, stiffness, and contractility may help reveal new biomarkers for diseases such as cancer and fibrosis.